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Different methods of radiometric dating vary in the timescale over which they are accurate and the materials to which they can be applied.
All ordinary matter is made up of combinations of chemical elements, each with its own atomic number, indicating the number of protons in the atomic nucleus.
Another possibility is spontaneous fission into two or more nuclides.
Additionally, elements may exist in different isotopes, with each isotope of an element differing in the number of neutrons in the nucleus.
A particular isotope of a particular element is called a nuclide. That is, at some point in time, an atom of such a nuclide will undergo radioactive decay and spontaneously transform into a different nuclide.
The basic equation of radiometric dating requires that neither the parent nuclide nor the daughter product can enter or leave the material after its formation.
The possible confounding effects of contamination of parent and daughter isotopes have to be considered, as do the effects of any loss or gain of such isotopes since the sample was created.